Our research interest

Proteins and protein complexes are molecular machines that participate and drive key biological events at the molecular level. The main focus of my lab is to understand important biological events and underlying molecular mechanisms by studying the structure of key proteins or protein complexes using X-ray crystallography and single particle cryo-electron microscopy (Cryo-EM). We are currently interested in structural studies of (1) centromere and kinetochore formation during mitosis, (2) histone chaperones as key epigenetic regulators, (3) human Sestrin2 as an mTORC1 regulator, and (4) methane monooxygenase to utilize natural gas as an alternative energy source.